منابع مشابه
Hungry codons promote frameshifting in human mitochondrial ribosomes.
Human mitochondria are not strict adherents to the universal genetic code, with modifications that include the apparent recoding of two arginine triplets to termination signals. This use of both AGA and AGG occurs rarely in other mammals, and this putative change has long posed a challenging conundrum. A -1 mitoribosome frameshift upstream of the rare codons would necessitate recognition of onl...
متن کاملRibosomes can slide over and beyond "hungry" codons, resuming protein chain elongation many nucleotides downstream.
In cells subjected to moderate aminoacyl-tRNA limitation, the peptidyl-tRNA-ribosome complex stalled at the "hungry" codon can slide well beyond it on the messenger RNA and resume translation further downstream. This behavior is proved by unequivocal amino acid sequence data, showing a protein that lacks the bypassed sequence encoded between the hungry codon and specific landing sites. The land...
متن کاملHippo - hungry, hungry for melanoma invasion
The acquisition of invasive properties in melanoma is associated with a high proclivity for metastasis, but the underlying pathways are poorly characterized. The Hippo pathway has an important role in organ size control and is dysregulated in some type of tumors. The present study, "Pro-invasive activity of the Hippo pathway effectors YAP and TAZ in cutaneous melanoma" by Nallet-Staub et al., 2...
متن کاملHungry for Rewards
talk a lot – but we also do so in very different ways. It would appear that the structure of a language is defined by its cultural ancestry and not by the way the brain processes language. A group of researchers at the Max Planck Institute for Psycholinguistics in Nijmegen in the Netherlands has analyzed the order of sentence parts in more than 300 languages from four major language families. T...
متن کاملFeeding a Hungry World
Dr. Daniel G. Aldrich, Jr.— first Chancellor of the University of California, Irvine, since January 19, 1962. Responsible for developing the campus from bare ground to a fully operating institution. Dr. Aldrich joined the University of California as a junior chemist in the Citrus Experiment Station at Riverside in 1943. Following three years of service in the armed forces during World War II, h...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2008
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1813rr5